Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) is a real-time, nanoscale technique for analyzing surface phenomena including thin film formation, interactions and reactions.

Quartz Crystal Microbalance with Dissipation Unit (QCM-D) – E4 (QSense) QCM-D can be used for real-time monitoring of the adsorption/desorption behaviour at the solid-liquid interface. Any kind of substrates e.g. nanometric cellulose thin films (amorphous, crystalline, nano/microfibrillar cellulose) can be employed for this purpose. Swelling characteristics can be monitored and the water uptake and water content of the films can be determined by D2O/H2O exchange studies. Changes in the supramolecular structure (e.g. by heat treatment, chemical treatment, adsorption of biopolymers) are usually accompanied in a change in water content and uptake. Also the viscoelastic properties of the films can be investigated. Suitable samples: model surfaces in dry, swollen and wet state.